CSUASOi006-A

Registration Summary:

A P E C

RP-PRPF8

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	CSUASOi006-A
Cite as:	CSUASOi006-A (RRID:CVCL_ZX46)
Alternative name(s)	RP-PRPF8
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	13th October 2020
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Provider
Generator	Aier School of Ophthalmology (CSUASO)
External iPSC Databases
Cellosaurus	CVCL_ZX46
Wikidata	Q102113728
General iPSC Information
Publications	Zhou Y et al. Establishment of non-integrate induced pluripotent stem cell line CSUASOi006-A, from urine-derived cells of a PRPF8-related dominant retinitis pigmentosa patient. Stem cell research. 2020 Dec;49:102041. Liang Yuqin et al. Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases. Stem Cell Research & Therapy. 2023-11-27. Yin X et al. Exploiting urine-derived induced pluripotent stem cells for advancing precision medicine in cell therapy, disease modeling, and drug testing. Journal of biomedical science. 2024 May 9;31(1):47. Yang HS et al. Application prospects of urine-derived stem cells in neurological and musculoskeletal diseases. World journal of orthopedics. 2024 Oct 18;15(10):918-931. Sun X et al. Generation of a gene-corrected isogenic human iPSC line (CSUASOi006-A-1) from a retinitis pigmentosa patient with heterozygous c.5792C > T mutation in the PRPF8 gene. Stem cell research. 2024 Dec;81:103572. Chen H et al. Generation of a human iPSC line with heterozygous PRPF8 c.5792C > T, p. T1931M mutation to model retinitis pigmentosa using CRISPR/Cas9 technology. Stem cell research. 2025 Apr;84:103689. Chen H et al. Generation of a gene-corrected isogenic human iPS cell line (CSUASOi006-A-2) from a retinitis pigmentosa patient using CRISPR/Cas9 technology. Stem cell research. 2025 Aug;86:103727. Sun X et al. PRPF8 Mutation-Induced Defects in Human iPSC-Derived RPE Are Rescued by Adenine Base Editing. Investigative ophthalmology & visual science. 2026 Jan 5;67(1):21.
Subclones	CSUASOi006-A-1 CSUASOi006-A-2

iPSC Derivation

General