INEUi002-A-1

PKP2 S140F

The cell line is not validated yet.

General

Cell Line

hPSCreg name INEUi002-A-1
Cite as:
INEUi002-A-1 (RRID:CVCL_C9LG)
Alternative name(s)
PKP2 S140F
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
INEUi002-A-2
(PKP2 KO)
INEUi002-A
(iPSC-FN2.1, FN2.1, FN2.1 WT)
ICANi002-A-5
(ICAN-PKP2-H695-W11)
INEUi002-A-7
(PKG-KO)
LUMCi027-A-1
(iso01LUMC0153iPKP03, LUMC0153iPKP03corr#22)
Donor's gene variants:
PKP2, PKP2
Donor diseases:
arrhythmogenic right ventricular dysplasia 9
UCSFi001-A-C
(AICS-0105-057)
UCSFi001-A-89
(AICS-0097-102)
UCSFi001-A-90
(AICS-0097-141)
UCSFi001-A-G
(AICS-0106-104)
UCSFi001-A-91
(AICS-0097-157)
UCSFi001-A-H
(AICS-0106-134)
UCSFi001-A-I
(AICS-0107-009)
UCSFi001-A-J
(AICS-0107-017)
UCSFi001-A-94
(AICS-0104-003)
UCSFi001-A-95
(AICS-0104-085)
UCSFi001-A-M
(AICS-0109-056)
UCSFi001-A-O
(AICS-0109-093)
UCSFi001-A-99
(AICS-0105-030)
UCSFi001-A-A
(AICS-0105-031)
UCSFi001-A-B
(AICS-0105-032)
UCSFi001-A-64
(P633L RBM20 iPSCs)
Last update 13th April 2026
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Provider

Generator Instituto de Neurociencias Conicet (INEU)

External Databases

Cellosaurus CVCL_C9LG
Wikidata Q123032702
BioSamples SAMEA120786565

General Information

Publications
* Is the cell line readily obtainable for third parties?
No
Subclone of

Donor Information

General Donor Information

Sex male
Ethnicity White Hispanic

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
No

External Databases (Donor)

BioSamples SAMEA120786167

Ethics

Also have a look at the ethics information for the parental line INEUi002-A .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line INEUi002-A.

Reprogramming method

Vector type None

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium Other medium:
Base medium: Stemflex
Main protein source:
Serum concentration: %
Has Rock inhibitor (Y27632) been used at passage previously with this cell line?
Yes
Has Rock inhibitor (Y27632) been used at cryo previously with this cell line?
Yes
Has Rock inhibitor (Y27632) been used at thaw previously with this cell line?
Yes

Characterisation

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
POU5F1 (OCT-4)
Yes
Morphology pictures
Differentiation Potency
Endoderm
Ont Id: UBERON_0000925
In vitro spontaneous differentiation
Marker Expressed
SOX17
Yes
Morphology
Cardiac Muscle Cell
Ont Id: CL_0000746
In vitro directed differentiation
Mesoderm
Ont Id: UBERON_0000926
In vitro spontaneous differentiation
Marker Expressed
TBX6
Yes
Ectoderm
Ont Id: UBERON_0000924
In vitro spontaneous differentiation
Marker Expressed
NES
Unknown
Morphology

Genotyping

Karyotyping (Cell Line)

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Synonyms
  • Cardiomyopathy
  • CARDIOMYOPATHY
  • Cardiomyopathy, NOS
Genetic modifications
PKP2 (target)
Variant
12p11.2
NM_001005242.3 (PKP2): c.419C>T
Homozygous