MLUi009-A

Registration Summary:

A P E C

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General

Cell Line
hPSCreg name	MLUi009-A
Cite as:	MLUi009-A (RRID:CVCL_D0IM)
Cell line type	Human induced pluripotent stem cell (hiPSC)
Similar lines	No similar lines found.
Last update	11th October 2022
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Provider
Generator	Medical Faculty of the Martin Luther University Halle-Wittenberg (MLU)
External Databases
Cellosaurus	CVCL_D0IM
Wikidata	Q123033076
General Information
Publications	Jung M et al. Generation of a set of induced pluripotent stem cell lines from two Alzheimer disease patients carrying APOE4 (MLUi007-J; MLUi008-A) and healthy old donors carrying APOE3 (MLUi009-A; MLUi010-B) to study APOE in aging and disease. Stem cell research. 2023 Jun;69:103072. Haferkamp U et al. Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease. Fluids and barriers of the CNS. 2023 Oct 31;20(1):78. Jung M et al. Neuronal Stem Cells from Late-Onset Alzheimer Patients Show Altered Regulation of Sirtuin 1 Depending on Apolipoprotein E Indicating Disturbed Stem Cell Plasticity. Molecular neurobiology. 2024 Mar;61(3):1562-1579. Xavier G et al. Comparison of Extracellular Vesicles from Induced Pluripotent Stem Cell-Derived Brain Cells. International journal of molecular sciences. 2024 Mar 22;25(7). Jothi D. et al. Strategies for modeling aging and age-related diseases. npj Aging. 2024-07-10.

hIPSC Derivation

General