SFC048-07-17

The cell line is not validated yet.

General

Cell Line

hPSCreg name STBCi098-C
Cite as:
STBCi098-C (RRID:CVCL_RD67)
Alternative name(s)
SFC048-07-17
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
STBCi098-A
(SFC048-07-14)
Donor diseases:
type 2 diabetes mellitus
STBCi098-B
(SFC048-07-18)
Donor diseases:
type 2 diabetes mellitus
STBCi100-A
(SFC117-03-01)
Donor diseases:
type 2 diabetes mellitus
STBCi107-A
(SFC104-03-01)
Donor diseases:
type 2 diabetes mellitus
STBCi110-A
(SFC116-03-01)
Donor's gene variants:
CFH
Donor diseases:
type 2 diabetes mellitus
age-related macular degeneration
STBCi122-A
(SFC115-03-01)
Donor diseases:
type 2 diabetes mellitus
STBCi126-A
(SFC105-03-01)
Donor diseases:
type 2 diabetes mellitus
STBCi127-A
(SFC107-03-01)
Donor diseases:
type 2 diabetes mellitus
CIRMi390-A
(CW70174)
Donor diseases:
type 2 diabetes mellitus
CIRMi391-A
(CW70175)
Donor diseases:
type 2 diabetes mellitus
CIRMi400-A
(CW70080)
Donor diseases:
type 2 diabetes mellitus
CIRMi434-A
(CW70230)
Donor diseases:
type 2 diabetes mellitus
UNEWi026-A
(SF116 clone 1)
Donor's gene variants:
CFH
Donor diseases:
type 2 diabetes mellitus
age-related macular degeneration
UNEWi026-B
(SF116 clone 2)
Donor's gene variants:
CFH
Donor diseases:
type 2 diabetes mellitus
age-related macular degeneration
UNEWi026-C
(SF116 clone K)
Donor's gene variants:
CFH
Donor diseases:
type 2 diabetes mellitus
age-related macular degeneration
CIRMi452-A
(CW70255)
Donor diseases:
type 2 diabetes mellitus
CIRMi454-A
(CW70257)
Donor diseases:
type 2 diabetes mellitus
CIRMi121-A
(CW50033)
Donor diseases:
type 2 diabetes mellitus
CIRMi465-A
(CW70269)
Donor diseases:
type 2 diabetes mellitus
CIRMi466-A
(CW70270)
Donor diseases:
type 2 diabetes mellitus
CIRMi467-A
(CW70272)
Donor diseases:
type 2 diabetes mellitus
CIRMi470-A
(CW70275)
Donor diseases:
type 2 diabetes mellitus
CIRMi475-A
(CW70281)
Donor diseases:
type 2 diabetes mellitus
CIRMi136-A
(CW50050)
Donor diseases:
type 2 diabetes mellitus
CIRMi477-A
(CW70283)
Donor diseases:
type 2 diabetes mellitus
CIRMi478-A
(CW70284)
Donor diseases:
type 2 diabetes mellitus
CIRMi486-A
(CW70298)
Donor diseases:
type 2 diabetes mellitus
CIRMi490-A
(CW70303)
Donor diseases:
type 2 diabetes mellitus
CIRMi491-A
(CW70304)
Donor diseases:
type 2 diabetes mellitus
CIRMi495-A
(CW70308)
Donor diseases:
type 2 diabetes mellitus
CIRMi500-A
(CW70315)
Donor diseases:
type 2 diabetes mellitus
CIRMi502-A
(CW70317)
Donor diseases:
type 2 diabetes mellitus
CIRMi503-A
(CW70318)
Donor diseases:
type 2 diabetes mellitus
CIRMi165-A
(CW50093)
Donor diseases:
type 2 diabetes mellitus
CIRMi510-A
(CW70325)
Donor diseases:
type 2 diabetes mellitus
CIRMi516-A
(CW70338)
Donor diseases:
type 2 diabetes mellitus
CIRMi520-A
(CW70343)
Donor diseases:
type 2 diabetes mellitus
CIRMi523-A
(CW70346)
Donor diseases:
type 2 diabetes mellitus
CIRMi532-A
(CW70358)
Donor diseases:
type 2 diabetes mellitus
CIRMi281-A
(CW70017)
Donor diseases:
type 2 diabetes mellitus
CIRMi536-A
(CW70366)
Donor diseases:
type 2 diabetes mellitus
CIRMi282-A
(CW70018)
Donor diseases:
type 2 diabetes mellitus
CIRMi537-A
(CW70368)
Donor diseases:
type 2 diabetes mellitus
CIRMi539-A
(CW70370)
Donor diseases:
type 2 diabetes mellitus
CIRMi540-A
(CW70371)
Donor diseases:
type 2 diabetes mellitus
CIRMi543-A
(CW70384)
Donor diseases:
type 2 diabetes mellitus
CIRMi291-A
(CW70034)
Donor diseases:
type 2 diabetes mellitus
CIRMi297-A
(CW70040)
Donor diseases:
type 2 diabetes mellitus
CIRMi299-A
(CW70042)
Donor diseases:
type 2 diabetes mellitus
Last update 31st May 2023
User feedback
No feedback available yet.

Login to share your feedback, experiences or results with the research community.

Provider

Generator StemBANCC (STBC)
Distributors

External Databases

BioSamples SAMEA104616150
EBiSC STBCi098-C
Cellosaurus CVCL_RD67
Wikidata Q54970238

General Information

Projects
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed

Donor Information

General Donor Information

Sex male

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Early onset familial Type 2 Diabetes
The donor is affected.
Synonyms
  • NIDDM
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
show more synonyms
Genetic variants
Early onset Familial T2D

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA104615907

Ethics

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? Yes
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Contact information / weblink zameel.cader@ndcn.ox.ac.uk
Is there other documentation provided to the donor for consenting purposes? No
Confirm that consent was obtained by a qualified professional Yes
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. pseudonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent expressly prevent the derivation of pluripotent stem cells? No
Does consent pertain to a specific research project? No
Does consent permit unforeseen future research, without further consent? Yes
Does consent expressly prevent development of commercial products? No
Does consent expressly prevent financial gain from any use of the donated embryo/tissue, including any product made from it? Yes
Does consent prevent the DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? Controlled Access
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Does the consent permit the donor, upon withdrawal of consent, to stop the use of the derived cell line(s) that have already been created from donated samples? No
Does the consent permit the donor, upon withdrawal of consent, to stop delivery or use of information and data about the donor? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? NRES Committee South Central - Hampshire A
Approval number 13/SC/0179
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells? Yes
Name of accrediting authority involved? NRES Committee South Central - Hampshire A
Approval number 13/SC/0179
Do you have obligations to third parties in regard to the use of the cell line? Yes
Please describe: DNA sequencing can only be performed for research into donors specified condition. Material shall not be sold, transplanted into any human being or used to create egg or sperm cells (gametes) or embryos. The material shall not be used for direct exploitation. For the purposes of this, Direct exploitation means to develop for commericalization or to commercialize the Material.
Are you aware of any further constraints on the use of the donated embryo/tissue or derived cells? No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

Source cell type
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.; These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Surface coating Matrigel/Geltrex
Feeder cells
No
Passage method Enzyme-free cell dissociation
EDTA
O2 Concentration 21 %
CO2 Concentration 5 %
Medium mTeSR™ 1

Characterisation

No characterisation data could be found.

Genotyping

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
No abnormalities detected
Karyotyping method: Molecular karyotyping by SNP array
http://

Other Genotyping (Cell Line)