UCSFi001-A-62

Registration Summary:

A P E C

The cell line is not submitted yet.

(only basic data is shown)

General

iPSC Line
hPSCreg name	UCSFi001-A-62
Cite as:	UCSFi001-A-62 (RRID:CVCL_C0IX)
iPSC line type	Human induced pluripotent stem cell (hiPSC)
Similar iPSC lines	No similar lines found.
Last update	20th December 2021
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Provider
Generator	Radboudumc - Department of Human Genetics (RMCGEN)
External iPSC Databases
Cellosaurus	CVCL_C0IX
Wikidata	Q112930510
General iPSC Information
Publications	Hommersom MP et al. Generation of induced pluripotent stem cell lines carrying monoallelic (UCSFi001-A-60) or biallelic (UCSFi001-A-61; UCSFi001-A-62) frameshift variants in CACNA1A using CRISPR/Cas9. Stem cell research. 2022 May;61:102730. Bozkaya-Yilmaz Sema et al. Phenotypic variability in cases with CACNA1A mutation. European Journal of Pediatrics. 2025-03-20. Hommersom MP et al. CACNA1A haploinsufficiency leads to reduced synaptic function and increased intrinsic excitability. Brain : a journal of neurology. 2025 Apr 3;148(4):1286-1301.
Subclone of	UCSFi001-A

iPSC Derivation

General
The source cell information can be found in the parental cell line UCSFi001-A.