Kolf 2.1 J (FUS R495X WT/SNV)

General

Cell Line

hPSCreg name WTSIi018-B-24
Cite as:
WTSIi018-B-24
Alternative name(s)
Kolf 2.1 J (FUS R495X WT/SNV)
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines
WTSIi018-B-25
(Kolf 2.1 J (FUS R495X SNV/SNV))
WTSIi018-B-26
(Kolf 2.1 J (FUS R521H WT/SNV))
WTSIi018-B-27
(Kolf 2.1 J (FUS R521H SNV/SNV))
WTSIi018-B
(HPSI0114i-kolf_2)
UCSFi001-A-74
(FUS-P525L HET 2D1)
UCSFi001-A-75
(FUS-P525L HOM 2D2)
UCSFi001-A-72
(FUS-R521G HET 2B10, LSUHSi004-A-72)
WTSIi018-B-21
(Kolf 2.1 J (TARDBP M337V SNV/SNV))
WTSIi018-B-22
(Kolf 2.1 J (TARDBP Q331K WT/SNV))
WTSIi018-B-23
(Kolf 2.1 J (TARDBP Q331K SNV/SNV))
WTSIi018-B-18
(Kolf 2.1 J (TARDBP M337V WT/SNV))
WTSIi018-B-1
(HPSI0114i-kolf_2-C1)
WTSIi018-A
(HPSI0114i-kolf_3)
UQi001-A-1
(C11-TDP43-A382T)
UCSFi001-A-73
(FUS-R521G HOM 1D9)
BIONi010-C-2
(BIONi010-C ApoE E3/E3 #H8 P32)
BIONi010-C-3
(BIONi010-C ApoE KO #KO30 P30)
BIONi010-C-25
(BIONi010-C heterozygous TREM2 KO)
BIONi010-C-6
(BIONi010-C ApoE E2/E2)
BIONi010-C-7
(BIONi010-C Trem2 R47H)
BIONi010-C-8
(BIONi010-C Trem2 T66M, #Y5-80)
BIONi010-C-9
(BIONi010-C CD33 KO)
BIONi010-C-17
(BIONi010-C TREM2 KO)
CBIGi001-A-1
(PRKN-KO, PRKN-KO/AIW002-02)
BIONi010-C-70
(BIONi010-C with an APOE 2/2 genotype with an additional, homozygous christchurch mutation)
BIONi010-C-71
(BIONi010-C with an APOE 3/3 genotype with an additional, homozygous christchurch mutation)
WAe001-A-76
(H1-RNF1-/-)
CBIGi001-A-2
(PINK1-KO, PINK1-KO/AIW002-02)
CBIGi001-A-3
(PINK1-KO/PRKN-KO/AIW002-02, PINK1-KO/PRKN-KO)
BIONi010-C-4
(BIONi010-C ApoE E4/E4 #B44 P27)
BIONi010-C-5
(BIONi010-C CD33 E2del #N14 P26)
Last update 5th March 2024
User feedback
No feedback available yet.

Login to share your feedback, experiences or results with the research community.

Provider

Generator Max Delbrück Center Berlin Buch (MDC)
Owner Jackson Laboratories (JAX)
Distributors
Derivation country United Kingdom

External Databases

BioSamples SAMEA115377739

General Information

Projects
* Is the cell line readily obtainable for third parties?
Yes
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed
Subclone of

Donor Information

General Donor Information

Sex male
Ethnicity White - White British

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
Yes

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA2398402
HipSci HPSI-kolf

Ethics

Also have a look at the ethics information for the parental line WTSIi018-B .
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation

General

The source cell information can be found in the parental cell line WTSIi018-B.

Reprogramming method

Vector type Non-integrating
Vector Sendai virus

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions

Medium Other medium:
Base medium: StemFlex
Main protein source:
Serum concentration: %

Characterisation

No characterisation data could be found for this subclone. Please open parental cell line WTSIi018-B .

Genotyping

Karyotyping (Cell Line)

Other Genotyping (Cell Line)

Genetic Modification

Disease/phenotype related modifications
Synonyms
  • Amyotrophic Lateral Sclerosis
  • ALS
  • Lou Gehrig Disease
  • Amyotrophic lateral sclerosis
show more synonyms
Genetic modifications
FUS (target)
Variant
chr16:31191052 (+)
Heterozygous