Drug discovery using human neurons

Title Drug discovery using human neurons
Acronym HumanNeuronScreen
Start date 2021-01-01
End date 2022-07-01
Sponsor European Research Council - Proof of Concept (ERC-PoC)
Institution Vrije Universiteit Amsterdam

Associated cell lines

Project Description

Neuromodulators are signaling molecules secreted by most neurons, which regulate many processes in our brain and body and dysregulation of neuromodulator secretion is firmly associated with many neurological and psychiatric disorders. With the HumanNeuronScreen neuromodulator secretion is measured in iPSC-derived neurons using high-end technology, thereby providing new methods for preclinical research towards treatments of neurological and psychiatric disorders.