EU-funded projects using hPSC

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  1. HybridRetina

    1st Nov 2017 - 1st Nov 2022

    Hybrid Retinal Prosthesis: High-Resolution Electrodes Array Integrated with Neurons for Restoration of Sight

    http://
    Associated cell lines:
  2. CellKarma

    1st Dec 2017 - 31st Oct 2022

    Dissecting the regulatory logic of cell fate reprogramming through integrative and single cell genomics

    http://
  3. ORGANOMICS

    1st Nov 2017 - 31st Oct 2022

    Reconstructing human cortex development and malformation with single-cell transcriptomics

    http://
  4. New-Chol

    1st Nov 2017 - 31st Oct 2022

    Development of New therapies against Cholangiopathies

    http://
  5. CerebralHominoids

    1st Oct 2017 - 1st Oct 2022

    Evolutionary biology of human and great ape brain development in cerebral organoids

    http://www2.mrc-lmb.cam.ac.uk/group-leaders/h-to-m/madeline-lancaster/
  6. LOGNEURODEV

    1st Oct 2017 - 30th Sep 2022

    The molecular and cellular logic of vertebrate neural development

    https://crick.ac.uk/research/a-z-researchers/researchers-a-c/james-briscoe/
  7. GenEdiDS

    1st Oct 2017 - 30th Sep 2022

    Rescuing Cognitive Deficits in Neurodevelopmental Disorders by Gene Editing in Brain Development: the case of Down syndrome

    https://www.iit.it/research/lines/local-micro-environment-and-brain-development
  8. EPiR

    1st Oct 2017 - 30th Sep 2022

    The Chemical Basis of RNA Epigenetics

    http://
    Associated cell lines:
  9. TYPHI

    1st Sep 2017 - 31st Aug 2022

    From typhoid fever to antimicrobial mechanisms

    http://
    Associated cell lines:
  10. REVERSEAUTISM

    1st Sep 2017 - 31st Aug 2022

    Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo and in vitro Models

    http://gnovarino.wixsite.com/novarino-lab
    Associated cell lines:
  11. LinPro

    1st Sep 2017 - 31st Aug 2022

    Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development

    http://
    Associated cell lines:
  12. MINERVA

    1st May 2017 - 30th Apr 2022

    MIcrobiota-Gut-BraiN EngineeRed platform to eVAluate intestinal microflora impact on brain functionality

    http://
  13. MICROGLIA-CIRCUIT

    1st Mar 2017 - 28th Feb 2022

    Microglia action towards neuronal circuit formation and function in health and disease

    http://ist.ac.at/research/life-sciences/siegert-group/
  14. CellNaivety

    1st Feb 2017 - 31st Jan 2022

    Deciphering the Molecular Foundations and Functional Competence of Alternative Human Naïve Pluripotent Stem Cells

    http://hannalabweb.weizmann.ac.il/
  15. SC-EpiCode

    1st Jan 2017 - 1st Jan 2022

    Decoding the Epigenomic Regulatory Code by the Use of Single Cell Technologies

    http://ramoren3.wixsite.com/oren-ram-lab
    Associated cell lines:
  16. SCP-hES

    1st Jan 2017 - 31st Dec 2021

    Mechanisms of spinal cord plasticity studied with hES cells

    http://
    Associated cell lines:
  17. MiniBrain

    1st Jan 2017 - 31st Dec 2021

    Cerebral Organoids: Using stem cell derived 3D cultures to understand human brain development and neurological disorders

    http://
    Associated cell lines:
  18. Mini Brains

    1st Jan 2017 - 31st Dec 2021

    Cerebral organoids: human mini brains in a dish open up new possibilities for drug development in neurodegenerative and developmental diseases

    http://
    Associated cell lines:
  19. PRIMATE-TE-IMPACT

    1st Nov 2016 - 31st Oct 2021

    Mapping the retrotransposon-mediated layer of neuronal gene regulation in the human genome

    http://www.frankjacobslab.com
    Associated cell lines:
  20. TRANSPOS-X

    3rd Jul 2016 - 2nd Jul 2021

    Transposable elements, their controllers and the genesis of human-specific transcriptional networks

    http://tronolab.epfl.ch
  21. PhaseAge-iPSC

    1st Apr 2017 - 31st Mar 2021

    Using genetically engineered iPSCs to model ALS

    https://www.mpi-cbg.de/research-groups/current-groups/simon-alberti/research-focus/
    Associated cell lines:
  22. StemProteostasis

    1st Mar 2016 - 28th Feb 2021

    Mediation of stem cell identity and aging by proteostasis

    http://vilchez.cecad-labs.uni-koeln.de/Home.545.0.html
    Associated cell lines:
  23. EPIROSE

    1st Jan 2016 - 31st Dec 2020

    Self-Organising Capacity of Stem Cells during Implantation and Early Post-Implantation Development: Implications for Human Development

    http://www.pdn.cam.ac.uk/zernickagoetzlab/
    Associated cell lines:
  24. RobustSynapses

    1st Jan 2016 - 31st Dec 2020

    ERC-2014-CoG - 646671 - Maintaining synaptic function for a healthy brain: Membrane trafficking and autophagy in neurodegeneration

    http://verstreken.vib.be
    Associated cell lines:
  25. REGMAMKID

    1st Nov 2015 - 31st Oct 2020

    How to regenerate the mammalian kidney

    http://www.ibecbarcelona.eu/iPSCs
    Associated cell lines:
  26. Training4CRM

    1st Nov 2016 - 31st Oct 2020

    European Training Network for Cell-based Regenerative Medicine

    http://
  27. INFANTLEUKEMIA

    1st Sep 2015 - 1st Sep 2020

    GENOMIC, CELLULAR AND DEVELOPMENTAL RECONSTRUCTION OF

    http://www.carrerasresearch.org/en/
    Associated cell lines:
  28. TE-ENHANCERs

    1st Jan 2016 - 31st Dec 2019

    Deciphering the roles of transposable elements in 3D genome architecture and gene expression

    http://tronolab.epfl.ch
    Associated cell lines:
  29. SPINDLE BRAIN ORGANOID

    1st Sep 2017 - 1st Sep 2019

    Role of spindle orientation in human brain development

    http://
    Associated cell lines:
  30. Schizophrenia Organoids

    1st Sep 2017 - 1st Sep 2019

    Understanding the role of parvalbumin interneuron development in schizophrenia using human cerebral organoids

    http://
    Associated cell lines:
  31. MASTFAST

    1st Sep 2017 - 28th Feb 2019

    Rapid Production of Human Mast Cells

    http://www.crm.ed.ac.uk/people/elaine-dzierzak
  32. BeyOND

    1st Feb 2014 - 31st Jan 2019

    Metabolic basis of neurodegenerative disease

    https://www.mdc-berlin.de/1149670/de/research/research_teams/molecular_cardiovascular_research
    Associated cell lines:
  33. BATCure

    1st Jan 2016 - 31st Dec 2018

    Developing new therapies for Batten disease

    http://
    Associated cell lines:
  34. EVERREST

    1st Jan 2013 - 31st Dec 2018

    Does vascular endothelial growth factor gene therapy safely improve outcome in severe early-onset fetal growth restriction?

    http://everrest-fp7.eu/
  35. STEMRD

    1st Nov 2013 - 31st Oct 2018

    Generation of stem cell derived photoreceptors for the treatment and modelling of retinal degeneration

    http://cordis.europa.eu/project/rcn/110795_en.html
  36. STEMCARDIOVASC

    1st Nov 2013 - 31st Oct 2018

    Human Pluripotent Stem Cells: the new heart patient?

    http://cordis.europa.eu/project/rcn/110774_en.html
  37. scientia fellows2016

    1st Sep 2016 - 31st Aug 2018

    DNMT3A and DNMT3B targeted mutations in hESC - interplay between non-coding RNAs and DNA methylation during human hematopoiesis

    http://www.med.uio.no/english/research/scientia-fellows/
    Associated cell lines:
  38. CAiPSC

    1st Sep 2016 - 31st Aug 2018

    Determining centromere assembly mechanisms and improving mitotic fidelity during somatic cell reprogramming

    http://sites.igc.gulbenkian.pt/epilab/
    Associated cell lines:
  39. CHROMATINRNA

    1st Sep 2013 - 31st Aug 2018

    The role of CpG island RNAs and Polycomb-RNA interactions in developmental gene regulation

    http://cordis.europa.eu/project/rcn/109713_en.html
  40. Cellphmed

    1st Feb 2017 - 1st Jul 2018

    Accurate cell signatures for the advancement of personalized medicine

    http://tronolab.epfl.ch/
    Associated cell lines:
  41. PD-HUMMODEL

    1st Jul 2013 - 30th Jun 2018

    Elucidating early pathogenic mechanisms of neurodegeneration in Parkinson's disease through a humanized dynamic in vitro model

    http://www.ub.edu/web/ub/en/recerca_innovacio/recerca_a_la_UB/projectes/fitxa/E/PE001011/informacioGeneral/index.html
    Associated cell lines:
  42. MwHresEP

    1st Jun 2017 - 31st May 2018

    Multi-well High-resolution Electrophysiology Platform

    http://
    Associated cell lines:
  43. EHT-CaMKII

    1st Apr 2016 - 31st Mar 2018

    CaMKII over stimulation in engineered heart tissues (EHTs) made from human induced pluripotent stem cells (hiPSCs): a parameter involved in the immaturity of hiPSC EHTs cardiomyocytes?

    Associated cell lines:
  44. PLURIMES

    1st Feb 2014 - 31st Jan 2018

    Pluripotent stem cell resources for mesodermal medicine

    http://www.plurimes.eu/
  45. NEUROSTEMCELLREPAIR

    1st Jan 2014 - 31st Dec 2017

    European stem cell consortium for neural cell replacement, reprogramming and functional brain repair

    http://www.neurostemcellrepair.org/
  46. HUMEN

    1st Jan 2014 - 31st Dec 2017

    Upscaling human insulin-producing beta cell production by efficient differentiation and expansion of endoderm progenitors

    http://cordis.europa.eu/projects/rcn/109474_en.html
  47. TRANSPOSOSTRESS

    1st Jan 2013 - 31st Dec 2017

    Impact of stress-induced transposon activities on human disease

    http://cordis.europa.eu/project/rcn/106732_en.html
  48. FORMAT

    1st Dec 2016 - 30th Nov 2017

    A novel medium for revolutionizing stem cell manufacturing technologies

    https://hannalabweb.weizmann.ac.il/
    Associated cell lines:
  49. RELIEVE-IMDS

    1st Dec 2012 - 30th Nov 2017

    Reprogramming cell identity to develop new therapies against Inherited Metabolic Disorders of the liver

    http://cordis.europa.eu/project/rcn/106273_en.html
  50. SEROTONINANDDISEASE

    1st Dec 2012 - 30th Nov 2017

    Dissecting the gene regulatory mechanisms that generate serotonergic neurons and their link to mental disorders

    http://cordis.europa.eu/projects/rcn/106220_en.html
  51. OTOSTEM

    1st Nov 2013 - 31st Oct 2017

    Human stem cell applications for the treatment of hearing loss

    http://www.otostem.org/
  52. THYMISTEM

    1st Oct 2013 - 30th Sep 2017

    Development of Stem Cell Based Therapy for Thymic Regeneration

    http://www.thymistem.org/
  53. REPAIR HD

    1st Oct 2013 - 30th Sep 2017

    Human pluripotent stem cell differentiation, safety and preparation for therapeutic transplantation in Huntington's disease

    http://www.repair-hd.eu/
    Associated cell lines:
  54. Scientia Fellows

    1st Sep 2015 - 31st Aug 2017

    The role of small non-coding RNAs during early mesoderm and hematopoietic differentiation

    http://www.med.uio.no/english/research/scientia-fellows/
    Associated cell lines:
  55. KidReg

    14th May 2015 - 31st May 2017

    Kidneyregeneration

    http://
    Associated cell lines:
  56. IDEA

    1st Mar 2012 - 28th Feb 2017

    Identification, homing and monitoring of therapeutic cells for regenerative medicine – Identify, Enrich, Accelerate

    http://cordis.europa.eu/project/rcn/102498_en.html
  57. DROPTECH

    1st Feb 2014 - 31st Jan 2017

    Hanging Drop based automated and parallelized cell technology platform for production and testing

    http://cordis.europa.eu/project/rcn/111381_en.html
  58. HipSci

    1st Jan 2013 - 31st Dec 2016

    HipSci

    http://www.hipsci.org/
  59. EBiSC

    1st Jan 2014 - 31st Dec 2016

    European bank of induced pluripotent stem cells

    http://www.ebisc.org/
  60. 4D-CellFate

    1st Dec 2011 - 30th Nov 2016

    Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation, in healthand disease

    http://www.4dcellfate.eu/content/4dcellfate-project-overview
    Associated cell lines:
  61. 4DCELLFATE

    1st Dec 2011 - 30th Nov 2016

    Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation, in health and disease

    http://www.4dcellfate.eu/
  62. CVGENES-AT-TARGET

    1st Oct 2013 - 30th Sep 2016

    Exploitation of genomic variants affecting coronary artery disease and stroke risk for therapeutic intervention

    http://cordis.europa.eu/project/rcn/110211_en.html
  63. OSTEOGROW

    1st Jan 2012 - 30th Jun 2016

    Novel Bone Morphogenetic Protein-6 Biocompatible Carrier Device for Bone Regeneration

    http://www.osteogrow.eu/
  64. HESUB

    1st May 2013 - 30th Apr 2016

    High Efficient, Single-Use-Bioreactor simulating mammalian tissue conditions for expression and proliferation

    http://hesub.eu/
    Associated cell lines:
  65. BLUEPRINT

    1st Oct 2011 - 31st Mar 2016

    A BLUEPRINT of Haematopoietic Epigenomes

    http://cordis.europa.eu/project/rcn/99677_en.html
  66. DDPDGENES

    1st Jan 2012 - 31st Dec 2015

    Identification of genes important for human midbrain dopamine neuron development and Parkinson's disease

    http://www.ddpdgenes.eu/
  67. SCR&TOX

    1st Jan 2011 - 31st Dec 2015

    Stem Cells for Relevant Efficient Extended and Normalized Toxicology

    http://www.scrtox.eu/
  68. TOXBANK

    1st Jan 2011 - 31st Dec 2015

    ToxBank ? Supporting Integrated Data Analysis and Servicing of Alternative Testing Methods in Toxicology

    http://cordis.europa.eu/project/rcn/97715_en.html
  69. TISSUEGEN

    1st Jan 2012 - 31st Dec 2015

    The production of a 3D human tissue disease platform to enable regenerative medicine therapy development

    http://www.tissuegen.org/
  70. DETECTIVE

    1st Jan 2011 - 31st Dec 2015

    Detection of endpoints and biomarkers of repeated dose toxicity using in vitro systems

    http://www.detect-iv-e.eu/
  71. NeuroGraft

    1st Dec 2012 - 30th Nov 2015

    Development of Functionalised Cell Seeded Bioartificial Organ for Transplantation in Nerve Repair

    http://neurograft.eu/
  72. AP-1-FUN

    1st Nov 2009 - 31st Oct 2015

    AP-1 (Fos/Jun) Functions in Physiology and Disease

    http://cordis.europa.eu/project/rcn/92530_en.html
  73. EPIHEALTH

    1st Nov 2011 - 31st Oct 2015

    Linking perturbed maternal environment during periconceptional development, due to diabetes, obesity or assisted reproductive technologies, and altered health during ageing

    http://epihealth.biotalentum.eu/
  74. EPIPGX

    1st Nov 2011 - 31st Oct 2015

    Epilepsy Pharmacogenomics: delivering biomarkers for clinical use

    http://www.epipgx.eu/
  75. EPIGENESYS

    1st Oct 2010 - 30th Sep 2015

    Epigenetics towards systems biology

    http://www.epigenesys.eu/en/
  76. NANOBIO4TRANS

    1st Sep 2012 - 31st Aug 2015

    A new nanotechnology-based paradigm for engineering vascularised liver tissue for transplantation

    http://www.nanobio4trans.eu/
  77. AFHELO

    1st Sep 2012 - 31st Aug 2015

    Preclinical proof of concept of AF243 potency to preventand/or treat sensorineural hearing loss

    http://www.afhelo.eu/
  78. AMBULUNG

    1st Jul 2012 - 30th Jun 2015

    Ambulatory Bio-Artificial Lung

    http://www.ambulung.com/
  79. ttt

    16th May 2015 - 17th May 2015

    Ich bin ein test

    http://
  80. kid

    14th May 2015 - 15th May 2015

    kidney

    http://
  81. EUROSTEMCELL

    1st Mar 2010 - 28th Feb 2015

    European Consortium for Communicating Stem Cell Research

    http://www.eurostemcell.org/
  82. MASC

    1st Jan 2010 - 31st Dec 2014

    Materials that Impose Architecture within Stem Cell Populations

    http://cordis.europa.eu/project/rcn/92783_en.html
  83. BETACELLTHERAPY

    1st Jan 2010 - 31st Dec 2014

    Beta Cell Therapy in Diabetes

    http://www.betacelltherapy.org/
  84. INNOVALIV

    1st Dec 2011 - 30th Nov 2014

    Innovative strategies to generate human hepatocytes for treatment of metabolic Liver diseases: Tools for personalized cell therapy

    http://www.innovaliv.eu/
    Associated cell lines:
  85. NCRNAX

    1st Apr 2009 - 31st Mar 2014

    Regulation and function of non-coding RNAs in epigenetic processes: the paradigm of X-chromosome inactivation

    http://cordis.europa.eu/project/rcn/89278_en.html
  86. ESNATS

    1st Apr 2008 - 30th Sep 2013

    Embryonic stem cell-based novel alternative testing strategies

    http://www.esnats.eu/
    Associated cell lines:
  87. NEUROSTEMCELL

    1st Dec 2008 - 31st May 2013

    European Consortium for Stem Cell Therapy for Neurodegenerative Diseases

    http://www.neurostemcell.org/
  88. BRAINCAV

    1st Oct 2008 - 31st Mar 2013

    Nonhuman adenovirus vectors for gene transfer to the brain

    http://cordis.europa.eu/project/rcn/88979_en.html
  89. BEST-STEM CELLS

    1st Jul 2009 - 31st Dec 2012

    Biochemically Equivalent Substitutive Technology for Stem Cells

    http://www.beststemcells.ed.ac.uk/
  90. CARDIOCELL

    1st May 2009 - 31st Oct 2012

    Development of cardiomyocyte replacement strategy for the clinic

    http://ec.europa.eu/research/health/medical-research/cardiovascular-diseases/index_en.html
  91. NEUROPRO

    1st Oct 2008 - 30th Sep 2012

    Oligopeptidase inhibitors in brain function and dysfunction: towards new therapeutic strategies for neuroprotection

    http://cordis.europa.eu/project/rcn/88499_en.html
  92. HYPERLAB

    1st Sep 2009 - 31st Aug 2012

    High yield and performance stem cell lab

    http://www.hyperlab.eu/
    Associated cell lines:
  93. PregVax

    1st Mar 2008 - 31st Aug 2012

    Plasmodium vivax Malaria in Pregnancy

    http://www.cresib.cat/en/page.asp?id=134
  94. INFARCT CELL THERAPY

    1st Jan 2009 - 30th Jun 2012

    Therapy after heart infarct: prevention of reperfusion injury and repair by stem cell transfer

    http://ec.europa.eu/research/health/medical-research/cardiovascular-diseases/index_en.html
  95. PLURISYS

    1st Jan 2009 - 30th Jun 2012

    Systems biology approaches to understand cell pluripotency

    http://plurisys.biotalentum.eu/
  96. HYPERGENES

    1st Jan 2008 - 31st Dec 2011

    European network for genetic-epidemiological studies: building a method to dissect complex genetic traits, using essential hypertension as a disease model

    http://www.hypergenes.eu/
  97. STEMEXPAND

    1st Nov 2008 - 31st Oct 2011

    Stem cell expansion - expansion and engraftment of haematopoietic and mesenchymal stem cells

    http://cordis.europa.eu/project/rcn/88520_en.html