XLC303, CSC-C00122

General#

Cell Line

hPSCreg Name CBi002-A
Alternative name(s)
XLC303, CSC-C00122
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 16th January 2018
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Provider

Generator Creative Bioarray (CB)

External Databases

BioSamples SAMEA103988342
Cellosaurus CVCL_IT52

General Information

Projects
Is the cell line available in principle? Available, without restrictions

Donor Information#

General Donor Information

Sex female
Ethnicity Caucasian

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
schizophrenia
The donor is affected.
Synonyms
  • Other specified types of schizophrenia, unspecified state
  • SCHIZOPHRENIA NEC-UNSPEC
  • Schizophrenia (disorder)
  • SCHIZO NEC-CHR/EXACERB
  • Unspecified schizophrenia (disorder)
  • Disorder, Schizophrenic
  • Other specified types of schizophrenia, chronic state
  • SCHIZO NEC-SUBCHR/EXACER
  • Schizophrenia, NOS
  • [X]Schizophrenia, unspecified
  • Unspecified schizophrenia, chronic state with acute exacerbation
  • schizophrenia-1
  • Unspecified schizophrenia, subchronic state with acute exacerbation
  • Schizophrenic Disorder
  • Schizophrenia NOS (disorder)
  • Schizophrenic Disorders
  • Other specified types of schizophrenia, subchronic state with acute exacerbation
  • Schizophrenia NOS
  • Dementia Praecox
  • SCHIZO NOS-CHR/EXACERB
  • Other specified types of schizophrenia, subchronic state
  • Unspecified schizophrenia, unspecified state
  • Other specified types of schizophrenia
  • Schizophrenic disorders (disorder)
  • Other specified types of schizophrenia, in remission
  • SCHIZOPHRENIA NEC-SUBCHR
  • SCHIZOPHRENIA NEC-CHR
  • SCHIZOPHRENIC DIS
  • Schizophrenias
  • [X]Schizophrenia, unspecified (disorder)
  • Unspecified schizophrenia
  • SCHIZOPHRENIA NEC-REMISS
  • SCHIZOPHRENIA NOS-UNSPEC
  • Disorders, Schizophrenic
  • SCHIZO NOS-SUBCHR/EXACER
  • Other specified types of schizophrenia, chronic state with acute exacerbation
show more synonyms
Disease associated phenotypes
  • schizo-affective disorder
Family history father also affected
Is the medical history available upon request? no
Is clinical information available? no

Karyotyping (Donor)

Has the donor karyotype been analysed?
Yes
46,XX

External Databases (Donor)

BioSamples SAMEA103988341

Ethics#

We are currently revising this section.

hIPSC Derivation#

General

Source cell type
fibroblast
A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
Age of donor (at collection) 25-29

Reprogramming method

Vector type Integrating

Vector free reprogramming

Other

Derived under xeno-free conditions
No
Derived under GMP?
No
Available as clinical grade?
No

Culture Conditions#

Feeder cells
Yes
Medium Other medium:
Base medium: DMEM
Main protein source: Knock-out serum replacement
Serum concentration: %

Characterisation#

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR FACS Enzymatic Assay Expression Profiles
NANOG
Yes
POU5F1 (OCT-4)
Yes
SOX2
Yes
DNMT3B
Yes
Alkaline Phosphatase
Unkown
Differentiation Potency

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Yes
46,XX

Other Genotyping (Cell Line)