UL1

General#

Cell Line

hPSCreg Name
MPIPi057-A
Alternative name(s)
UL1
Cell line type Human induced pluripotent stem cell (hiPSC)
Last update 14th April 2022
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Provider

Generator Max Planck Institute of Psychiatry (MPIP)

External Databases

BioSamples SAMEA13855412

General Information

Projects
* Is the cell line readily obtainable for third parties?
No

Donor Information#

General Donor Information

Sex unknown

Phenotype and Disease related information (Donor)

Diseases A disease was diagnosed.
Progressive myoclonic epilepsy type 1
Synonyms
  • Unverricht-Lundborg disease
  • Progressive myoclonus epilepsy type 1
  • ULD
  • EPM1
show more synonyms

External Databases (Donor)

BioSamples SAMEA13846808

Ethics#

Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Provide contact information of the holder of the original Donor Information Sheet: Laura.Canafoglia@istituto-besta.it
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Contact information / weblink Laura.Canafoglia@istituto-besta.it
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? No information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? Yes
Name of accrediting authority involved? LMU
Approval number 19-635
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation#

General

Source cell line name PBMC
Derived from same source line (potentially other lot and donor, see below):
Source cell type
Peripheral Blood Mononuclear Cell
A peripheral blood cell with a single nucleus. This category includes lymphocytes and monocytes.
Synonyms
  • PERIPHERAL BLOOD MONONUCLEAR CELL
  • Peripheral Blood Mononuclear Cell
  • Peripheral Blood Mononuclear cells
  • PBMC
show more synonyms

Reprogramming method

Vector type Non-integrating
Vector Episomal

Vector free reprogramming

Other

Derived under xeno-free conditions
Unknown
Derived under GMP?
Unknown
Available as clinical grade?
Unknown

Culture Conditions#

Medium TeSR™ E8™

Characterisation#

Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR FACS Enzymatic Assay Expression Profiles
NES
Yes
PAX6
Yes
SOX2
Yes
TUBB3
Yes
TRA 1-60
Yes
Score:
Marker Present Absent
mCpG
OCT4
Differentiation Potency
Neuroepithelial Stem Cell
Ont Id: CL_0002259

Genotyping#

Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Unknown

Other Genotyping (Cell Line)