A Gene Therapy for Resynchronization of Cardiac Conduction in Pacing-Induced Cardiomyopathy

Title A Gene Therapy for Resynchronization of Cardiac Conduction in Pacing-Induced Cardiomyopathy
Acronym SYNCHROPACE
Start date 2021-11-01
End date 2024-11-01
Sponsor Horizon 2020 (H2020)
Institution University of Amsterdam - Academic Medical Center

Associated cell lines

Project Description

A first-ever cardiac Gene Therapy Medicinal Product (GTMP) to treat pacing-induced cardiomyopathy (PICM). Our technique involves a proprietary technology to restore ion channels in the heart to generate and resynchronize cardiac pacing function. A GTMP’s safety and efficacy package in line with authorities will allow the compilation and submission of a CTA / IND within 9 months after the project will be concluded.