A Gene Therapy for Resynchronization of Cardiac Conduction in Pacing-Induced Cardiomyopathy
| Title | A Gene Therapy for Resynchronization of Cardiac Conduction in Pacing-Induced Cardiomyopathy |
|---|---|
| Acronym | SYNCHROPACE |
| Start date | 2021-11-01 |
| End date | 2024-11-01 |
| Sponsor | Horizon 2020 (H2020) |
| Institution | University of Amsterdam - Academic Medical Center |
Associated cell lines
Publications
Project Description
A first-ever cardiac Gene Therapy Medicinal Product (GTMP) to treat pacing-induced cardiomyopathy (PICM). Our technique involves a proprietary technology to restore ion channels in the heart to generate and resynchronize cardiac pacing function. A GTMP’s safety and efficacy package in line with authorities will allow the compilation and submission of a CTA / IND within 9 months after the project will be concluded.