Cell Line

hPSCreg name UOSi001-B
Cite as:
UOSi001-B (RRID:CVCL_1E70)
Alternative name(s)
Cell line type Human induced pluripotent stem cell (hiPSC)
Similar lines No similar lines found.
Last update 22nd May 2019
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Generator University of Sheffield (UOS)
Derivation country United Kingdom

External Databases

Cellosaurus CVCL_1E70
BioSamples SAMEA5424900
Wikidata Q54953347

General Information

* Is the cell line readily obtainable for third parties?
Research use: allowed
Clinical use: not allowed
Commercial use: not allowed

Donor Information

General Donor Information

Sex male
Age of donor (at collection) neonate
Ethnicity Caucasian, White

Phenotype and Disease related information (Donor)

Diseases No disease was diagnosed.

Other Genotyping (Donor)

Is there genome-wide genotyping or functional data available?
SNP typing array

Donor Relations

Other cell lines of this donor

External Databases (Donor)

BioSamples SAMEA103885930


Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived? Yes
Was the consent voluntarily given? Yes
Has the donor been informed that participation will not directly influence their personal treatment? Yes
Can you provide us with a copy of the Donor Information Sheet provided to the donor? No
Provide contact information of the holder of the original Donor Information Sheet: http://www.lgcstandards-atcc.org/en/Support/LGC_Contact_Us.aspx
Do you (Depositor/Provider) hold the original Donor Consent Form? No
If you do not hold the Donor Consent Form, do you know who does? Yes
Contact information / weblink http://www.lgcstandards-atcc.org/en/Support/LGC_Contact_Us.aspx
Alternatives to consent are available? Yes
Alternatives to consent
Alternative consent approval number
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised. anonymised
Does consent explicitly allow the derivation of pluripotent stem cells? Yes
Does consent expressly prevent the derivation of pluripotent stem cells? No
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world? No
How may genetic information associated with the cell line be accessed? No information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions? No
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells? No
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?

hIPSC Derivation


Source cell line name CCD-1112Sk
Other names
Derived from same source line (potentially other lot and donor, see below):
Source cell type
Dermal fibroblasts are the major cell type in dermis and are commonly accepted as terminally differentiated cells.
Source cell origin
A retractable double-layered fold of skin and mucous membrane that covers the glans penis and protects the urinary meatus when the penis is not erect.
  • prepuce
  • preputium
  • penile prepuce
  • prepuce of male
  • preputium penis
  • foreskin
  • praeputium
  • prepucium
show more synonyms
Age of donor (at collection) neonate
Source cell line vendor ATCC

Reprogramming method

Vector type None

Vector free reprogramming

Type of used vector free reprogramming factor(s)


Selection criteria for clones morphology
Derived under xeno-free conditions
Derived under GMP?
Available as clinical grade?

Culture Conditions

Surface coating Gelatin
Feeder cells mouse embryonic fibroblast
Cellfinder Ont Id: CF_43885
Passage method Enzymatically
O2 Concentration 21 %
CO2 Concentration 5 %
Medium Other medium:
Base medium: DMEM/F12
Main protein source: Knock-out serum replacement
Serum concentration: 20 %


Analysis of Undifferentiated Cells
Marker Expressed Immunostaining RT-PCR Flow Cytometry Enzymatic Assay Expression Profiles
POU5F1 (OCT-4)
TRA 1-81
Differentiation Potency
Ont Id: UBERON_0000925
In vivo teratoma
In vitro spontaneous differentiation
Ont Id: UBERON_0000926
In vivo teratoma
In vitro spontaneous differentiation
Ont Id: UBERON_0000924
In vivo teratoma
In vitro spontaneous differentiation


Karyotyping (Cell Line)

Has the cell line karyotype been analysed?
Karyotyping method: G-Banding

Other Genotyping (Cell Line)