Development of culture conditions for the differentiation of hES cells into hepatocytes
Title | Development of culture conditions for the differentiation of hES cells into hepatocytes |
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Acronym | LIV-ES |
Website | http://www.liv-es.eu/index.php?option=com_frontpage&Itemid=1 |
Start date | 2008-10-01 |
End date | 2012-03-31 |
Sponsor | European Union's Seventh Framework Programme (FP7) |
Associated cell lines
Project Description
Liver transplantation is currently the only available, effective treatment for people with life-threatening metabolic disorders and acute liver failure. However, shortage of organ donors and long-term complications such as hypertension, diabetes or obesity represent major restrictions to widespread application of liver transplantation. There is therefore a clear need for viable alternatives such as cell-based therapies. LIV-ES’ goal is to develop innovative conditions and standardized protocols to provide a renewable source of human hepatocytes (liver cells) for the treatment of liver diseases.