Development of culture conditions for the differentiation of hES cells into hepatocytes

Title Development of culture conditions for the differentiation of hES cells into hepatocytes
Acronym LIV-ES
Website http://www.liv-es.eu/index.php?option=com_frontpage&Itemid=1
Start date 2008-10-01
End date 2012-03-31
Sponsor European Union's Seventh Framework Programme (FP7)

Associated cell lines

Project Description

Liver transplantation is currently the only available, effective treatment for people with life-threatening metabolic disorders and acute liver failure. However, shortage of organ donors and long-term complications such as hypertension, diabetes or obesity represent major restrictions to widespread application of liver transplantation. There is therefore a clear need for viable alternatives such as cell-based therapies. LIV-ES’ goal is to develop innovative conditions and standardized protocols to provide a renewable source of human hepatocytes (liver cells) for the treatment of liver diseases.