The cell line is
not validated yet.
General Donor Information
Phenotype and Disease related information (Donor)
A disease was diagnosed.
Disease associated phenotypes
Facial dysmorphisms: Full nasal tip with thick columella, Full lower tip; Neurologic features: Behavioral problems (ADHD), sleeping problems, progressive torsion dystonia; Development: Mild intellectual disability; Other: Hemihypotrophy of distal part of left leg, dysphagia, Hypermetropia, Oesophageal atresia with TE fistula
External Databases (Donor)
Has informed consent been obtained from the donor of the embryo/tissue from which the pluripotent stem cells have been derived?
Was the consent voluntarily given?
Has the donor been informed that participation will not directly influence their personal treatment?
Can you provide us with a copy of the Donor Information Sheet provided to the donor?
Provide contact information of the holder of the original Donor Information Sheet:
Do you (Depositor/Provider) hold a copy of the SIGNED Donor Consent Form?
If you do not hold the SIGNED Donor Consent Form, do you know who does?
If you do not hold the SIGNED Donor Consent Form, have you obtained a copy of the unsigned Donor Consent Form from the holder?
Please indicate whether the data associated with the donated material has been pseudonymised or anonymised.
Does consent explicitly allow the derivation of pluripotent stem cells?
Does consent prevent CELLS DERIVED FROM THE DONATED BIOSAMPLE from being made available to researchers anywhere in the world?
Policy for access to genetic information
Will the donor expect to receive financial benefit, beyond reasonable expenses, in return for donating the biosample?
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the Research Protocol including the consent provisions?
Name of accrediting authority involved?
Has a favourable opinion been obtained from a research ethics committee, or other ethics review panel, in relation to the PROPOSED PROJECT, involving use of donated embryo/tissue or derived cells?
For generation of the cell line, who was the supplier of any recombined DNA vectors or commercial kits used?
Source cell type
Human B-lymphoblastoid cell line transformed by Epstein-Barr (EBV-LCLs) Virus.
Is reprogramming vector detectable?
Vector free reprogramming
Derived under xeno-free conditions
Derived under GMP?
Available as clinical grade?
Has Rock inhibitor (Y27632) been used at passage previously with this cell line?
Has Rock inhibitor (Y27632) been used at cryo previously with this cell line?
Has Rock inhibitor (Y27632) been used at thaw previously with this cell line?
Analysis of Undifferentiated Cells
Karyotyping (Cell Line)
Has the cell line karyotype been analysed?
Other Genotyping (Cell Line)