Derivation of a human DOA iPSC line, IISHDOi006-A, with a mutation in the ACO2 gene: c.1999G>A; p.Glu667Lys
Summary
Human iPSC line, IISHDOi006-A, was obtained from fibroblasts of a patient with Dominant Optic Atrophy (DOA) carrying a heterozygous mutation in the gene ACO2: c.1999G>A; p.Glu667Lys. Reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc were delivered using a non-integrative methodology that involves the use of Sendai virus. Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Cerrada V, García-López M, Moreno-Izquierdo A, Villaverde C, Zurita O, Martin-Merida MI, Arenas J, Ayuso C, Gallardo ME |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2019 Oct;40:101566 |
| PubMed | 31509793 |
| DOI | 10.1016/j.scr.2019.101566 |