Generation of 5 hiPSC lines derived from three unrelated idiopathic Parkinson disease patients and two unrelated healthy control individuals


We describe generation of human induced pluripotent stem cell (hiPSC) lines of three unrelated idiopathic late onset Parkinson disease patients and two healthy controls above 60 years of age without neurological diseases nor Ashkenazi ancestry. Human iPSC were derived from peripheral blood-erythroblasts using integration free episomal plasmids carrying four reprogramming factors OCT4, SOX2, c-MYC, KLF4 and BCL-XL. The hiPSC lines were characterized according to established criteria. Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Tofoli FA, Chien HF, Barbosa ER, Pereira LV
Journal Stem cell research
Publication Date 2019 Dec;41:101640
PubMed 31710912
DOI 10.1016/j.scr.2019.101640

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