Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi003-A) from a Wilson's disease patient harboring a homozygous R778L mutation in ATP7B gene


Human IPSC Line, ZZUNEUi003-A, was generated from a 32-year-old male patient with Wilson's Disease carrying a homozygous R778L mutation in ATP7B gene, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype. Copyright © 2019 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Zhang J, Wei L, Chen D, Feng L, Wu C, Wang R, Li X
Journal Stem cell research
Publication Date 2019 Dec;41:101664
PubMed 31783295
DOI 10.1016/j.scr.2019.101664

Research Projects

Cell Lines