Generation of an induced pluripotent stem cell line SYSUi-003-A from a child with epilepsy carrying GRIN2A mutation


We generated iPSCs from peripheral blood mononuclear cells of a child with epilepsy carrying heterozygous missense mutation in GRIN2A, using integration free episomal vectors. These iPSCs express pluripotent markers, represent a normal karyotype and have the ability to differentiate into three germ layers. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Sun C, Yang M, Qin F, Guo R, Liang S, Hu H
Journal Stem cell research
Publication Date 2020 Mar;43:101706
PubMed 32036246
DOI 10.1016/j.scr.2020.101706

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