Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene


Human IPSC Line, ZZUNEUi004-A, was generated from a 34-year-old male patient with Wilson's Disease carrying a homozygous Pro992Leu mutation in ATP7B gene, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Zhang J, Wei L, Chen D, Feng L, Wu C, Wang R, Li X, Liu H
Journal Stem cell research
Publication Date 2020 Apr;44:101741
PubMed 32113134
DOI 10.1016/j.scr.2020.101741

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