Analysis of multi-lineage gene expression dynamics during primordial germ cell induction from human induced pluripotent stem cells


During PGCLC induction process in vitro, the differentiating embryoids not only activated the PGC-related genes, but also displayed complex regulation of pluripotency genes and multi-lineage genes. These results would be meaningful for future research investigating the regulation of human early germ line development.

Authors Fang F, Li Z, Zhao Q, Xiong C, Ni K
Journal Stem cell research & therapy
Publication Date 2020 Mar 4;11(1):100
PubMed 32127035
PubMed Central PMC7055065
DOI 10.1186/s13287-020-01620-y

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