Analysis of multi-lineage gene expression dynamics during primordial germ cell induction from human induced pluripotent stem cells
Summary
During PGCLC induction process in vitro, the differentiating embryoids not only activated the PGC-related genes, but also displayed complex regulation of pluripotency genes and multi-lineage genes. These results would be meaningful for future research investigating the regulation of human early germ line development.
| Authors | Fang F, Li Z, Zhao Q, Xiong C, Ni K |
|---|---|
| Journal | Stem cell research & therapy |
| Publication Date | 2020 Mar 4;11(1):100 |
| PubMed | 32127035 |
| PubMed Central | PMC7055065 |
| DOI | 10.1186/s13287-020-01620-y |