Generation of two control iPSC clones NCCSi008-A and NCCSi008-B from an individual of Indian ethnicity
Summary
Two iPSC clones, NCCSi008-A and NCCSi008-B, were generated from a healthy male individual of Indian origin by reprogramming his CD4+ T cells with an integration free Sendai viral vector. The established iPSC clones showed high alkaline phosphatase (ALP) activity, expression of pluripotency markers, a normal male karyotype consistent with the donor gender (46, XY) and has potential for multi-lineage differentiation. These iPSC lines of Indian origin would serve as valuable resources for disease modeling, drug development and screening. Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Vaidyanath A, Khan M, Shiras A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2020 May;45:101765 |
| PubMed | 32315960 |
| DOI | 10.1016/j.scr.2020.101765 |