Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration


Age-related macular degeneration (AMD) is a late-onset progressive blinding disease. We established human induced pluripotent stem cells (iPSCs) from an AMD patient. The generated iPSC line showed pluripotency markers and three-germ layer differentiation ability in vitro. This iPSC line will be useful for elucidating the pathomechanisms of and drug discovery for AMD. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Kamata K, Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Yasukawa T, Usui H, Muguruma K, Tsujikawa A, Inoue H
Journal Stem cell research
Publication Date 2020 May;45:101787
PubMed 32416577
DOI 10.1016/j.scr.2020.101787

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