Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration
Summary
Age-related macular degeneration (AMD) is a late-onset progressive blinding disease. We established human induced pluripotent stem cells (iPSCs) from an AMD patient. The generated iPSC line showed pluripotency markers and three-germ layer differentiation ability in vitro. This iPSC line will be useful for elucidating the pathomechanisms of and drug discovery for AMD. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Kamata K, Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Yasukawa T, Usui H, Muguruma K, Tsujikawa A, Inoue H |
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| Journal | Stem cell research |
| Publication Date | 2020 May;45:101787 |
| PubMed | 32416577 |
| DOI | 10.1016/j.scr.2020.101787 |