Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration
Age-related macular degeneration (AMD) is a late-onset progressive blinding disease. We established human induced pluripotent stem cells (iPSCs) from an AMD patient. The generated iPSC line showed pluripotency markers and three-germ layer differentiation ability in vitro. This iPSC line will be useful for elucidating the pathomechanisms of and drug discovery for AMD. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
|Authors||Kamata K, Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Yasukawa T, Usui H, Muguruma K, Tsujikawa A, Inoue H|
|Journal||Stem cell research|
|Publication Date||2020 May;45:101787|