Generation of an iPSC line (CHWi001-A) from peripheral blood mononuclear cells in a patient with intellectual disability and haploinsufficiency of PLPPR4

Summary

Intellectual disability (ID) is a highly inherited neurodevelopmental disorder. A human induced pluripotent stem cell (iPSC) line was generated from peripheral blood mononuclear cells (PBMCs) in a patient with intellectual disability and carrying a haploinsufficiency for PLPPR4. This iPSC line offers a useful resource to investigate the pathogenesis and molecular mechanisms involved in PLPPR4-related ID. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Wan R, Zhang Q, Li H, Xu X, Tang S
Journal Stem cell research
Publication Date 2020 May 1;45:101811
PubMed 32388443
DOI 10.1016/j.scr.2020.101811

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