Generation of an iPSC line (CHWi001-A) from peripheral blood mononuclear cells in a patient with intellectual disability and haploinsufficiency of PLPPR4
Summary
Intellectual disability (ID) is a highly inherited neurodevelopmental disorder. A human induced pluripotent stem cell (iPSC) line was generated from peripheral blood mononuclear cells (PBMCs) in a patient with intellectual disability and carrying a haploinsufficiency for PLPPR4. This iPSC line offers a useful resource to investigate the pathogenesis and molecular mechanisms involved in PLPPR4-related ID. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Wan R, Zhang Q, Li H, Xu X, Tang S |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2020 May;45:101811 |
| PubMed | 32388443 |
| DOI | 10.1016/j.scr.2020.101811 |