Establishment of a human induced pluripotent stem cell (iPSC) line (JUCTCi010-A) from a healthy Jordanian female skin dermal fibroblasts
Summary
Human integration-free induced pluripotent pluripotent stem cells (hiPSCs) were generated from skin fibroblasts obtained from a 27-year-old healthy Jordanian female. The resulting iPSCs expressed the most common pluripotency stem cell markers, they retained the normal karyotype similar to the original fibroblasts and showed the potential to differentiate into three germ layers in vitro. This iPSC line could serve as a wild-type control that can be used in hereditary disease modeling studies and in optimization of different differentiation protocols. Copyright © 2020. Published by Elsevier B.V.
| Authors | Ababneh NA, Al-Kurdi B, Ali D, Abuarqoub D, Barham R, Salah B, Awidi A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2020 Jun 24;47:101891 |
| PubMed | 32622344 |
| DOI | 10.1016/j.scr.2020.101891 |