Establishment and characterization of two iPSC lines derived from healthy controls


We have generated two iPSC lines from skin biopsies of two healthy individuals. Skin fibroblasts were derived and reprogrammed using a Sendai virus-based approach. The resulting iPSC lines have normal karyotype, express stemness markers and can generate endoderm, mesoderm and ectoderm in vitro. These iPSC lines can be used as healthy controls in differentiation paradigms as well as backbone for gene editing experiments. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Patel A, Garcia Diaz A, Moore JC, Sirabella D, Corneo B
Journal Stem cell research
Publication Date 2020 Jul 25;47:101926
PubMed 32738631
DOI 10.1016/j.scr.2020.101926

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