Generation of a human induced pluripotent stem cell (iPSC) line (JUCTCi011-A) from skin fibroblasts of a healthy Jordanian male subject

Summary

Human induced pluripotent stem cell line (JUCTCi011-A) was generated from skin fibroblasts obtained from a 34-year-old healthy male subject from Jordan. The generated iPSCs showed typical embryonic-like characteristics. They retained their normal karyotype similar to their parental dermal fibroblast cells, expressed pluripotency markers and showed a differentiation potential into three germ layers as demonstrated by immunostaining and flow cytometry. This generated cell line can be used in disease modeling studies, to serve as a healthy control line and to help in developing novel therapeutic strategies for patients with hereditary neuromuscular diseases. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Ababneh NA, Al-Kurdi B, Ali D, Barham R, Sharar N, Mrahleh MM, Salah B, Awidi A
Journal Stem cell research
Publication Date 2020 Jul 31;48:101923
PubMed 32771906
DOI 10.1016/j.scr.2020.101923

Research Projects

Cell Lines