Generation of a human induced pluripotent stem cell (iPSC) line (JUCTCi011-A) from skin fibroblasts of a healthy Jordanian male subject
Summary
Human induced pluripotent stem cell line (JUCTCi011-A) was generated from skin fibroblasts obtained from a 34-year-old healthy male subject from Jordan. The generated iPSCs showed typical embryonic-like characteristics. They retained their normal karyotype similar to their parental dermal fibroblast cells, expressed pluripotency markers and showed a differentiation potential into three germ layers as demonstrated by immunostaining and flow cytometry. This generated cell line can be used in disease modeling studies, to serve as a healthy control line and to help in developing novel therapeutic strategies for patients with hereditary neuromuscular diseases. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Ababneh NA, Al-Kurdi B, Ali D, Barham R, Sharar N, Mrahleh MM, Salah B, Awidi A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2020 Oct;48:101923 |
| PubMed | 32771906 |
| DOI | 10.1016/j.scr.2020.101923 |