Generation of human induced pluripotent stem cell line UNIGEi003-A from skin fibroblasts of an apparently healthy male donor
Summary
Dermal fibroblasts isolated from an apparently healthy 50-year-old man were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The generated iPSC line has been expanded under feeder-free conditions and displayed all hallmarks of a standard pluripotent stem cell line such as a normal karyotype, expression of pluripotent factors and differentiation capacity into the three germ layers. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
Authors | Cosset E, Vannary T, Sloan-Béna F, Gimelli S, Gerstel E, Krause KH, Marteyn A |
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Journal | Stem cell research |
Publication Date | 2020 Oct;48:101928 |
PubMed | 32805538 |
DOI | 10.1016/j.scr.2020.101928 |