Impact of the DSP-H1684R Genetic Variant on Ion Channels Activity in iPSC-Derived Cardiomyocytes
Summary
Our results show that desmoplakin genetic variants, besides conduction slowing caused by structural heart remodeling, could affect multiple ion channel activity aggravating arrhythmia manifestation in PCCD. © Copyright by the Author(s). Published by Cell Physiol Biochem Press.
| Authors | Gusev K, Khudiakov A, Zaytseva A, Perepelina K, Makeenok S, Kaznacheyeva E, Kostareva A |
|---|---|
| Journal | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology |
| Publication Date | 2020 Jul 25;54(4):696-706 |
| PubMed | 32706220 |
| DOI | 10.33594/000000249 |