Impact of the DSP-H1684R Genetic Variant on Ion Channels Activity in iPSC-Derived Cardiomyocytes


Our results show that desmoplakin genetic variants, besides conduction slowing caused by structural heart remodeling, could affect multiple ion channel activity aggravating arrhythmia manifestation in PCCD. © Copyright by the Author(s). Published by Cell Physiol Biochem Press.

Authors Gusev K, Khudiakov A, Zaytseva A, Perepelina K, Makeenok S, Kaznacheyeva E, Kostareva A
Journal Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Publication Date 2020 Jul 25;54(4):696-706
PubMed 32706220
DOI 10.33594/000000249

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