Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system
Summary
Urinary cells can be an ideal source for generating hiPSCs and progenitors, as they are easily accessible, non-invasive, and universally available. We generated human induced pluripotent stem cells (hiPSCs) from the urinary cells of a healthy donor using a Sendai virus-based gene delivery method. The generated hiPSC line, KSCBi001-A, has a normal karyotype (46,XY). The pluripotency and capacity of multilineage differentiation were characterized by comparison with those of a human embryonic stem cell line. This cell line is registered and available from National Stem Cell Bank, Korea National Institute of Health. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Uhm KO, Jo EH, Go GY, Kim SJ, Choi HY, Im YS, Ha HY, Jung JW, Koo SK |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2017 May;21:44-46 |
| PubMed | 28677537 |
| DOI | 10.1016/j.scr.2017.03.019 |