Generation of the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor


Human pluripotent stem cells (hiPSC) are highly valuable tools to model lung development and chronic bronchial diseases. We generated a hiPSC line from a highly characterized 40-year-old healthy male nonsmoking donor. Peripheral blood mononuclear cells (PBMCs) were reprogrammed using integration-free Sendai Virus. The cell line had normal karyotype, expressed pluripotency hallmarks, and differentiated into the three primary germ layers. The reported UHOMi002-A iPSC line may be used as a control to model lung development, study human chronic bronchial diseases and drug testing. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Fieldes M, Ahmed E, Bourguignon C, Mianné J, Martin M, Arnould C, Vachier I, Assou S, De Vos J, Bourdin A
Journal Stem cell research
Publication Date 2020 Dec;49:102037
PubMed 33099111
DOI 10.1016/j.scr.2020.102037

Research Projects

Cell Lines