Generation of the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor
Summary
Human pluripotent stem cells (hiPSC) are highly valuable tools to model lung development and chronic bronchial diseases. We generated a hiPSC line from a highly characterized 40-year-old healthy male nonsmoking donor. Peripheral blood mononuclear cells (PBMCs) were reprogrammed using integration-free Sendai Virus. The cell line had normal karyotype, expressed pluripotency hallmarks, and differentiated into the three primary germ layers. The reported UHOMi002-A iPSC line may be used as a control to model lung development, study human chronic bronchial diseases and drug testing. Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Fieldes M, Ahmed E, Bourguignon C, Mianné J, Martin M, Arnould C, Vachier I, Assou S, De Vos J, Bourdin A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2020 Dec;49:102037 |
| PubMed | 33099111 |
| DOI | 10.1016/j.scr.2020.102037 |