Generation of an induced pluripotent stem cell (iPSC) line (THSJTUi001-A) from a Wilson's disease patient harboring a homozygous Arg778Leu mutation in ATP7B gene
Summary
Induced pluripotent stem cell (iPSC) line, THSJTUi001-A, was generated from a 26-year-old Chinese male patient with Wilson's disease carrying a homozygous Arg778Leu mutation in ATP7B gene, using non-integrated episomal reprogramming vectors. This cell line had normal karyotype, expressed pluripotency markers and could differentiate into the three germ layers in vivo. Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Wang SH, Wang XP |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2020 Dec;49:102050 |
| PubMed | 33096383 |
| DOI | 10.1016/j.scr.2020.102050 |