Generation of the iPSC line IISHDOi007-A from peripheral blood mononuclear cells from a patient with McArdle disease harbouring the mutation c.2392 T > C; p.Trp798Arg
Summary
Peripheral blood mononuclear cells (PBMCs) from a McArdle patient carrying a homozygous mutation in the PYGM gene: c.2392 T > C; p.Trp798Arg were used for the generation of the human iPSC line, IISHDOi007-A. For the delivery of the reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc, a non-integrative methodology that implies the use of Sendai virus has been applied. Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Cerrada V, García-López M, Alvarez-Galeano S, Moreno-Izquierdo A, Lucia A, Rabasa Pérez M, Arenas J, Gallardo ME |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2020 Dec;49:102108 |
| PubMed | 33370875 |
| DOI | 10.1016/j.scr.2020.102108 |