An induced pluripotent stem cells line (ZZUNEUi022-A) derived from urine cells of healthy male human


Urine cells (or renal tubular cells) can be isolated from human urine samples efficiently. This noninvasive and cost-effective method to collect biological sample provide us favorable access to donor cells from human. In the present study, we generate ZZUNEUi022-A, a urine cells-derived induced pluripotent stem cell (iPSC) line, from a 29-year-old healthy male via Sendai virus delivery system. ZZUNEUi022-A showed stable karyotype, and could differentiate into three germ layers (ectoderm, mesoderm, and endoderm) readily in an embryoid body formation model. Copyright © 2021. Published by Elsevier B.V.

Authors Liu Y, Li X, Fu W, Liu M, Wang M, Hu L, Wang L, Zhao X, Ding Z, Dong J
Journal Stem cell research
Publication Date 2021 Mar;51:102191
PubMed 33529980
DOI 10.1016/j.scr.2021.102191

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