Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor


Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs line exhibits a normal karyotype, expresses stemness markers and displays the differentiation capacity into the three germ layers. This human iPSCs line can be used as healthy control in disease modelling studies. Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Bono F, Mutti V, Piovani G, Minelli A, Mingardi J, Guglielmi A, Missale C, Gennarelli M, Fiorentini C, Barbon A
Journal Stem cell research
Publication Date 2021 Mar;51:102216
PubMed 33548809
DOI 10.1016/j.scr.2021.102216

Research Projects

Cell Lines