Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor
Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs line exhibits a normal karyotype, expresses stemness markers and displays the differentiation capacity into the three germ layers. This human iPSCs line can be used as healthy control in disease modelling studies. Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.
|Authors||Bono F, Mutti V, Piovani G, Minelli A, Mingardi J, Guglielmi A, Missale C, Gennarelli M, Fiorentini C, Barbon A|
|Journal||Stem cell research|
|Publication Date||2021 Jan 29;51:102216|