Establishment and characterization of induced pluripotent stem cell (iPSCs) line UNIBSi014-A from a healthy female donor
Summary
Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs line exhibits a normal karyotype, expresses stemness markers and displays the differentiation capacity into the three germ layers. This human iPSCs line can be used as healthy control in disease modelling studies. Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Bono F, Mutti V, Piovani G, Minelli A, Mingardi J, Guglielmi A, Missale C, Gennarelli M, Fiorentini C, Barbon A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2021 Mar;51:102216 |
| PubMed | 33548809 |
| DOI | 10.1016/j.scr.2021.102216 |