Generation of a hiPSC line ZZUNEUi017-A from a patient with dilated cardiomyopathy caused by mutation in TTN
Dilated cardiomyopathy (DCM) is the commonest type of cardiomyopathy. In this study, peripheral blood mononuclear cells (PBMCs) were isolated from a DCM patient with the p. Glu12513fs(c.37537delG) mutation in TTN and were reprogrammed to human induced pluripotent stem cells (iPSCs). The ZZUNEUi017-A iPSC line expressed pluripotency markers, exhibiting a normal male karyotype (46, XY) and demonstrating differentiation potential into three germ layers in vitro. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.
|Authors||Huang S, Fu W, Guo G, Tiana X, Zhao X, Dong J, Li X, Yang H|
|Journal||Stem cell research|
|Publication Date||2021 Feb 15;52:102248|