Generation of integration-free induced pluripotent stem cells from healthy individuals


Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6-18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc. Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Yde Ohki CM, Grossmann L, Döring C, Hoffmann P, Herms S, Werling AM, Walitza S, Grünblatt E
Journal Stem cell research
Publication Date 2021 May;53:102269
PubMed 33667761
DOI 10.1016/j.scr.2021.102269

Research Projects

Cell Lines