Generation of an iPSC line (ZZUNEUi016-A) derived from a hypertrophic cardiomyopathy patient with the heterozygote mutation in MYH7 gene

Summary

HCM is one of the most common inheritable cardiac disease. In our study, we established a human-induced pluripotent stem cells (hiPSCs) line (ZZUNEUi016-A) from a hypertrophic cardiomyopathy patient with the pathogenic heterozygote mutation in MYH7 gene. ZZUNEUi016-A expressed pluripotency markers with normal karyotype and showed the ability to differentiate into all three germ layers in vitro. Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Guo G, Fu W, Li X, Dong J, Zhao X, Zhang Y
Journal Stem cell research
Publication Date 2021 Feb 18;53:102262
PubMed 33636496
DOI 10.1016/j.scr.2021.102262

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