Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient
Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male familial Alzheimer's disease patient carrying the T119I mutation in the PSEN1 gene. PSEN1 genotype was maintained and stemness and pluripotency confirmed in the FLENIi001-A hiPSC line. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.
|Authors||Isaja L, Rodríguez-Varela MS, Marazita M, Mucci S, Itzcovich T, Chrem-Méndez P, Niikado M, Ferriol-Laffouillere SL, Allegri R, Martinetto H, Sevlever GE, Scassa ME, Surace EI, Romorini L|
|Journal||Stem cell research|
|Publication Date||2021 Apr 5;53:102325|