Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation
In this study we describe the generation and characterization of an human induced pluripotent stem cell (hiPSC) line from a long QT syndrome type 1 (LQT1) patient carrying the KCNQ1 c.940 G > A (p.Gly314Ser) mutation. This patient-specific iPSC line has been obtained by using non-integrational Sendai reprogramming method, expresses pluripotency markers and has the capacity to differentiate into the three germ layers and into spontaneously beating cardiomyocytes (iPSC-CMs). Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.
|Authors||Lavra L, Magi F, Ulivieri A, Morgante A, Paulis M, Sala L, Pedrazzini M, Polisca P, Rocchetti M, Calò L, Sciacchitano S, Salehi LB|
|Journal||Stem cell research|
|Publication Date||2021 Jul;54:102418|