Human iPSC-derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model


Altogether, these results strongly suggest that iPSC-NPCs transplantation induces neuroprotection and functional recovery in a mouse model of HD and should be taken forward for clinical trials in HD patients. © 2021 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd.

Authors Park HJ, Jeon J, Choi J, Kim JY, Kim HS, Huh JY, Goldman SA, Song J
Journal Cell proliferation
Publication Date 2021 Aug;54(8):e13082
PubMed 34152047
PubMed Central PMC8349664
DOI 10.1111/cpr.13082

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