Human iPSC-derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model
Summary
Altogether, these results strongly suggest that iPSC-NPCs transplantation induces neuroprotection and functional recovery in a mouse model of HD and should be taken forward for clinical trials in HD patients. © 2021 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd.
| Authors | Park HJ, Jeon J, Choi J, Kim JY, Kim HS, Huh JY, Goldman SA, Song J |
|---|---|
| Journal | Cell proliferation |
| Publication Date | 2021 Aug;54(8):e13082 |
| PubMed | 34152047 |
| PubMed Central | PMC8349664 |
| DOI | 10.1111/cpr.13082 |