Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus vector system


The defective and persistent Sendai virus (SeVdp) vector system allows efficient generation of transgene-free induced pluripotent stem cells (iPSCs) from human somatic cells. By leveraging the system, here we report the generation of an iPSC line from somatic fibroblasts of a healthy control donner (female), named KEIOi002-A (also named YG-iPS). The control iPSC line would be a useful resource for stem cell research and regenerative medicine. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Zhou Z, Yoshimatsu S, Qian E, Ishikawa M, Sato T, Ohtaka M, Nakanishi M, Okano H
Journal Stem cell research
Publication Date 2021 Oct;56:102549
PubMed 34598113
DOI 10.1016/j.scr.2021.102549

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