Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus vector system

Summary

The defective and persistent Sendai virus (SeVdp) vector system allows efficient generation of transgene-free induced pluripotent stem cells (iPSCs) from human somatic cells. By leveraging the system, here we report the generation of an iPSC line from somatic fibroblasts of a healthy control donner (female), named KEIOi002-A (also named YG-iPS). The control iPSC line would be a useful resource for stem cell research and regenerative medicine. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Zhou Z, Yoshimatsu S, Qian E, Ishikawa M, Sato T, Ohtaka M, Nakanishi M, Okano H
Journal Stem cell research
Publication Date 2021 Sep 23;56:102549
PubMed 34598113
DOI 10.1016/j.scr.2021.102549

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