Generation of induced pluripotent stem cell Line KAIMRCi001-A by reprogramming erythroid progenitors from peripheral blood of a healthy Saudi donor
Summary
In this study we isolated and enriched erythroid progenitor cells (EPCs) from a 10 ml peripheral blood sample from a 37-year old healthy Saudi donor. After expansion, these EPCs were reprogrammed using episomal plasmids to generate an induced pluripotent stem (iPS) cell line, KAIMRCi001-A. The pluripotency of this line was confirmed by measuring the expression of typical pluripotency markers and assessing differentiation potential in vitro. Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Al-Shehri M, Baadhaim M, Jamalalddin S, Aboalola D, Daghestani M, AlZahrani H, Malibari D, Mubaraki M, Aldubayan K, AlBalwi M, Alsayegh K |
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| Journal | Stem cell research |
| Publication Date | 2021 Oct;56:102548 |
| PubMed | 34592601 |
| DOI | 10.1016/j.scr.2021.102548 |