Generation of iPSC line MU011.A-hiPS from homozygous α-thalassemia fetal skin fibroblasts

Summary

Human iPSC line MU011.A-hiPS was generated from homozygous α-thalassemia (-(SEA)/-(SEA)) fetal skin fibroblasts using a non-integrative reprogramming method. Reprogramming factors OCT3/4, SOX2, KLF4, L-MYC, LIN28, and shRNA of TP53 contained in three episomal vectors were delivered using electroporation. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Tangprasittipap A, Satirapod C, Jittorntrum B, Lertritanan S, Anurathaphan U, Phanthong P, Borwornpinyo S, Kitiyanant N, Hongeng S
Journal Stem cell research
Publication Date 2015 Nov;15(3):506-9
PubMed 26432158
DOI 10.1016/j.scr.2015.09.003

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