Generation of a human induced pluripotent stem cell line from a patient diagnosed with schizophrenia carrying a 16p11.2 deletion


16p11.2 copy number variations have been associated with neurodevelopmental disorders. Human induced pluripotent stem cells were generated from fibroblasts obtained from a patient diagnosed with schizophrenia with a 16p11.2 deletion. The generated cell line was further validated for its pluripotency and potential to differentiate into the three germ layers. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Madencioglu DA, Kruth K, Shin M, Andreasen N, Wassink T, Williams A
Journal Stem cell research
Publication Date 2021 Dec 21;59:102636
PubMed 34953327
DOI 10.1016/j.scr.2021.102636

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