Generation of a human induced pluripotent stem cell line from a patient diagnosed with schizophrenia carrying a 16p11.2 deletion
Summary
16p11.2 copy number variations have been associated with neurodevelopmental disorders. Human induced pluripotent stem cells were generated from fibroblasts obtained from a patient diagnosed with schizophrenia with a 16p11.2 deletion. The generated cell line was further validated for its pluripotency and potential to differentiate into the three germ layers. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Madencioglu DA, Kruth K, Shin M, Andreasen N, Wassink T, Williams A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2022 Mar;59:102636 |
| PubMed | 34953327 |
| PubMed Central | PMC9209596 |
| DOI | 10.1016/j.scr.2021.102636 |