Generation of iPSC line FAMRCi010-A from patient with restrictive cardiomyopathy carrying genetic variant FLNC p.Gly2011Arg
Summary
Human iPSC cell line FAMRCi010-A was generated from a patient with restrictive cardiomyopathy carrying FLNC p.Gly2011Arg genetic variant. Patient-specific peripheral blood mononuclear cells were reprogrammed using non-integrative Sendai viruses containing OCT4, SOX2, KLF4, and CMYC. FAMRCi010-A was generated and characterized through the study. The reported iPSC line could be useful tool for in vitro modeling of FLNC-associated cardiomyopathies. Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Perepelina K, Khudiakov A, Rodina N, Boytsov A, Vavilova T, Zlotina A, Sokolnikova P, Kostareva A |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2022 Mar;59:102639 |
| PubMed | 34971931 |
| DOI | 10.1016/j.scr.2021.102639 |