Establishment of SIAISi018-A, an induced pluripotent stem cell (iPSC) line from a healthy 45-year-old Chinese Han

Summary

A 45-year-old Han Male from China contributed peripheral blood mononuclear cells induced by reprogramming human OKSM transcription factors (OCT3/4, KLF4 SOX2 and C-MYC) with a non-integrated additional vector system. Immunological markers confirmed the pluripotent nature of IPSC. Spontaneous tridermal differentiation confirmed the differentiation ability of IPSC with normal karyotype. Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Zhang Y, Shou J, Gu W, Di W, Zhao J, Wang Y, Gu S
Journal Stem cell research
Publication Date 2022 Apr;60:102659
PubMed 35124538
DOI 10.1016/j.scr.2022.102659

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