The chemokine CXCL14 mediates platelet function and migration via direct interaction with CXCR4
Summary
Our results reveal CXCL14 as a novel platelet-derived chemokine that is involved in thrombus formation and platelet migration. Furthermore, we identified CXCR4 as principal receptor for CXCL14, an interaction promoting platelet migration. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.
| Authors | Witte A, Rohlfing AK, Dannenmann B, Dicenta V, Nasri M, Kolb K, Sudmann J, Castor T, Rath D, Borst O, Skokowa J, Gawaz M |
|---|---|
| Journal | Cardiovascular research |
| Publication Date | 2021 Feb 22;117(3):903-917 |
| PubMed | 32239134 |
| DOI | 10.1093/cvr/cvaa080 |