Generation of a human iPSC line, INMi005-A, from a patient with non-syndromic USH2A-associated retinitis pigmentosa
We report here the generation of the human iPSC line INMi005-A from a patient with non-syndromic autosomal recessive retinitis pigmentosa caused by compound heterozygous mutations in the USH2A gene. The reprogramming of primary human dermal fibroblasts was performed using the non-integrative Sendai virus method and the OSKM transcription factor cocktail. The generated INMi005-A iPSC line is pluripotent and genetically stable, and will represent a valuable tool for understanding the pathophysiology associated with USH2A mutations. Copyright © 2022. Published by Elsevier B.V.
|Authors||Sanjurjo-Soriano C, Erkilic N, Vache C, Dubois G, Roux AF, Meunier I, Kalatzis V|
|Journal||Stem cell research|
|Publication Date||2022 Apr;60:102738|