Generation of integration-free induced pluripotent stem cell line (KSCBi012-A) from urinary epithelial cells of a healthy male individual
Summary
A human induced pluripotent cell (hiPSC) line, KSCBi012-A, was generated from a 40-year-old male individual using non-integrating episomal vectors expressing reprogramming factors. The generated hiPSCs were integration-free, expressed pluripotency markers, exhibited the potential for differentiation into three germ layers in vivo, and maintained the normal karyotype. This cell line can be used as a control for a disease model and is available from Korea National Stem Cell Bank. Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Im YS, Yoo DH, Kim HE, Oh JY, Kim YO |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2022 Aug;63:102841 |
| PubMed | 35700632 |
| DOI | 10.1016/j.scr.2022.102841 |