Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes
Summary
Fibroblasts drive Aldoc-mediated metabolic reprogramming and rhythmic regulation in SANs. This work details the cellular machinery behind the complex milieu of vertebrate SANs and opens a new direction for future therapy.
| Authors | Chou PC, Liu CM, Weng CH, Yang KC, Cheng ML, Lin YC, Yang RB, Shyu BC, Shyue SK, Liu JD, Chen SP, Hsiao M, Hu YF |
|---|---|
| Journal | Circulation research |
| Publication Date | 2022 Jun 24;131(1):6-20 |
| PubMed | 35611699 |
| DOI | 10.1161/circresaha.121.320301 |